Povidone Iodine

Lets discuss most commonly used solution in surgery "Povidone iodine (Betadine)"-
It is available in 5% & 10% solution, 7/5% W/V ointment and also as mouth wash
Iodine is a good germicidal and is effective against Virus, bacteria, protozoa, Fungi and yeast but it is irritant, insoluble and instable.

To overcome all these problems it is mixed with Polyvinyl Pyrrolidone, thus it becomes Povidone iodine. Now it has bactericidal properties and water soluble yet nontoxic.

• The povidone carrier releases its iodine slowly.

• Iodophors are highly effective but their anti-microbial action declines rapidly upon drying, (does not have a residual effect).

• Iodine is in-activated by organic material so should be applied only to clean skin

• Loss of colour of solution denotes loss of bactericidal properties.
 

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